DrMKZ

1. BMPR2 imbalnce vasoconstric and vasodilator

2.Left ventricular heart failure – back flow into pulmonary veins -> increase PCWP -> back flow pressure pulmonary congestion

3. Type 3 – intense pulmonary hypoxia, chronic interstiasial lung disase – poorly oxygenated blood – chronic hypoxaemia – pulmonary vasocontriction

4. CTEPH- clots within their pulmonary artery- pulmonary emboli chronic. – flow disturbs

5. Type multifactorial causes- > strain

RV strain

Right ventricular pressure

-> portal venous pressures, perritoneal cappilary pressure -> interstial space -. ascites low SAAG

-> lower extremites -> edema

Right heart diffulcit to go to the left heart.

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presentation

dyspnea

syncope and exertional symptoms

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